Intern, Clinical Genetics Portfolio Analyst
Who We Are
From research and discovery to post-market clinical development, our WWRD engine involves all bench and clinical research and the associated groups that support those endeavors. Our teams work on developing first-in-class and best-in-class therapeutics that provide meaningful advances to patients who live with genetic diseases.
SUMMARY:
The BioMarin Summer Internship Program will enable students to gain valuable experience and knowledge of the processes and systems within BioMarin, while gaining an insight into the pharmaceutical/biotech industry.
Experimental Medicine lies within the Early Clinical Development Team of Worldwide R&D at BioMarin Pharmaceutical Inc.The BioMarin R&D portfolio relies heavily on genetic and genomic expertise in cardiac, non-oncology hematologic, CNS, metabolic, and musculoskeletal therapeutic areas.Using gene, oligonucleotide, peptide, biologic, and small-molecule therapies, BioMarin addresses unmet patient needs, focusing on diseases with four core attributes: genetic, targeted, assessable, and transformational.
JOB DESCRIPTION/PROJECT:
THE CLINICAL GENETICS PORTFOLIO ANALYST POSITION INVOLVES IN-DEPTH REVIEW OF CLINICAL AND MOLECULAR GENETIC ASPECTS OF DISEASES ACROSS THE EARLY CLINICAL DEVELOPMENT PIPELINE.THE AIMS ARE TO ANALYZE GENOTYPE-PHENOTYPE CORRELATION, PARSE PATIENTS INTO CLINICALLY MEANINGFUL SUBGROUPS MOST LIKELY TO BENEFIT SAFELY FROM THERAPIES, AND TO UNDERSTAND THE CLINICAL GENETIC EPIDEMIOLOGY OF THE TARGET DISEASE.THE CLINICAL GENETICS PORTFOLIO ANALYST WILL WORK CLOSELY WITH THE CLINICAL GENETICS TEAM TO RESEARCH GENETIC MECHANISMS OF DISEASE, PARTICULAR MUTATION TYPES THAT AFFECT PHENOTYPE AND INFORM PATIENT SELECTION FOR CLINICAL TRIALS, AND STRATEGIES FOR PATIENT IDENTIFICATION AND RELEVANT BIOMARKERS OF DISEASE PROGRESSION AND THERAPEUTIC RESPONSE.
REQUIRED SKILLS:
- Graduate level knowledge of genetics and molecular biology
- Ability to comprehend published medical and population genetics research
- Familiarity with fundamental clinical genetic databases such as ClinVar, gnomAD, etc.
- Strong writing, presentation, and verbal communication skills
DESIRED SKILLS:
- CLINICAL EXPERIENCE WITH GENETIC SYNDROMES
- PRIOR PUBLICATION OF CLINICAL GENETIC CASE REPORTS OR PRIMARY RESEARCH
- ABILITY TO COLLATE, ANALYZE, AND ENTER DATA IN SPREADSHEETS
- GRADUATE LEVEL COURSEWORK IN GENETICS (DEGREE OR IN CLINICAL GENETICS RESIDENCY)
QUALIFICATIONS/ELIGIBILITY:
- Early career or in-training MD, MD/PhD, or PhD molecular geneticist; highly qualified MD or PhD student with interest in clinical genetics career/pharmaceutical research
- Student must be returning to school in the Fall Term OR has graduated within the 1 year of the start of the program.
- Must be available to work 40 hours a week
- Must be authorized to work in the United States without visa sponsorship
BENEFITS OF A BIOMARIN INTERNSHIP:
- Apply skills and knowledge learned in the classroom to on-the-job experiences
- Comprehensive, value-added project(s)
- Work in teams and with colleagues in a professional environment.
- Develop skills specific to your major.
- Opportunities for professional development by building relationships and learning about other parts of the business.
In the U.S., the salary range for this position is $ 30.00 to $ 50.00 per hour, which factors in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors.
Equal Opportunity Employer/Veterans/Disabled
An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.